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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '910a5d45773257e73e332a9b7b215aeac1c92d7132a68b4cbf8843d824151ac5' 
  AND token = '+xf13VTr1RaFW1OKu63YouMpbL/f1ewj4jLE6SpgxwA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}