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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f2b16a2cab4a38688b40d2fc111145e8e1044a11ca6508ec6621b90a9b1fa070' 
  AND token = 'cU/r69RtUdhe0jyWNCG3Q1bLleLTQYIHQ5a0xRtT8sM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}