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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ef1fe2c55414b7ee229727b0292a0e91c07068b74cfcee6c683194a775150b93' 
  AND token = 'mObdVWk9Q5e/NF4lje4r1Dw269c/V6eBqtrmhnsCbYM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}