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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1c4d71ce770df996789e5366be6fbfb536ea4fc7c83d31292d5b9dd33ae09c0c' 
  AND token = 'gVtybdutR/rHScQDhwv1Gru/1Spk9VZw7UwrwbDjF3k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}