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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd15062d2cc99c064c8891ccdf1ac6c199a7a6b81b604a5f4617e80e23276b15b' 
  AND token = 'EJtwhI/yigXYPMjSCf5Vp2weXMOhW1PgG8bZM79A/uw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}