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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3b40c1fca4188be04b988325b15fa278c9455b89277735e56f6865f5aceff96a' 
  AND token = 'LzQk4+nW2q7py43wutgQwDOr3n4sxfGonajrMMYpKQE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}