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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1c5df8ee7e4f781b362c97c6aa6c7614c8ff1dee0ff1698e0dc7528dc0812af5' 
  AND token = 'XbxmYM4oWFY/HPQEHnJwLnCEllr4HvJXYFaRqiBtE64=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}