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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '58e26be4bb7a1eb4d46ebba4416a52fa8bb0407b6bc001f585c0252340c0640a' 
  AND token = 'lo+Nkqu4Kjp5KpXTt7MfzEibJCQ80nRQheI4+QhYdcE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}