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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9645ba453d838e6ec4aa88158f2e8700ffa892eb26f02066b7023cfc4ca42d33' 
  AND token = 'xsFzXkhzfoE0AtUSySpcDF+L1/q1OPNBH8EtC7ukOMA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}