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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7d0ff50d6d82335ed5cdfd801d25ca0dfdd793d2a960476b83840475f9ce3be1' 
  AND token = '70eLBNAe9qZGQk5+Nn2xBVw4hWfbZoNcRiTSKrDNdWI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}