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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'acace9db5fbf764b479c4137c4d331b8399aef828a892b57bb75da0c399eb8b3' 
  AND token = '5cD0053k52QjDxoVqZWIRG+PWcmbvd9ptnPdfwHcK7k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}