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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '05a716f53acd4078d5d704fe761d63ad8fdfa8b5b121b29494ab8bfe7bde9ac4' 
  AND token = 'dy1I4mbbyEpqVGn1yR6jq0kGq2p7u/UstzwHWF5dCWA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}