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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b7c9a621b903386ab1b7697de8900b7275cda8aa367571346d9e6c27910f57bd' 
  AND token = 'KnpL4Vte7uRyh2nljue4DT7aKjsL1X1vpUSP2V8KfNY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}