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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eba0c4d1e23d3522a476f2155684e14c1b46b1baec0fc84fae9ae4c215b18016' 
  AND token = 'tb3Mv4UwGqKMt16bALvDLkxZUQ0EBhqLYfoCOlBzmlY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}