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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8599b650b0001d488fcbda949d86477338ed4c59c40d73c0e6a1c18fa677afa6' 
  AND token = '8Mj4MkyRGzYZ6N9955YXXm0DFoz1KxmYO422tSYXIdk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}