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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9e176ebff914e8f89a6f22f0684117eb8832a38418ffc5aba3d97aaf7341771f' 
  AND token = 'ETRLhckB1hGE6mThSE/g8GynkOmY/hZI2ghrnswVV2Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}