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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ef67574d38c500593207293f412e6f9bcefafe80716424ded39a9f748a3d22a' 
  AND token = '6a9tncOuDZo1tXdsLiU7TkbvFqWItUZC643+WqRprwI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}