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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e9cdf36890ed72cb40dbaac209bd028fa0cceebea1f00854f3c4829ee5428f7d' 
  AND token = 'r/P/2efQREcOsav6cuNkKbtlFr5/uikNBo8A5K9UY2Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}