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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d403103dc6d48406fe33e0a3e89b82c98b4c08933aa3d2beb968163a241511c' 
  AND token = 'TRs9LTWNBzSwXm5I1bjJ5RV3XUZHndWuoEPd9w7L04Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}