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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '58c0b44abec940e56d545c5b53fec7d96e58a68de17ba91dc30110f287e537e9' 
  AND token = 'HUmOQcRvTlJ+BIx9gRGRB1+ThjcDpG0/6ekUHfeuMU4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}