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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1ebc50f6ba68ce63f9fa9cc987329da11513e318988031b028a73d73b0aaa456' 
  AND token = 'qCJWbJYbQN2OH/CfPGeYmw2L8fAeJgBsqgceZNCCwLk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}