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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '66260cecaee4da339ca457590e76f4372d80b1b284b52618e9caac0d917f911d' 
  AND token = 'HAX0ex3qbgPcAc4DHaPi42YzhndGrIU2OcfkZnVmajE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}