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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '86b6d6626f0726ecc5f50c0294c77c0fdd0e8511a40badd410e3ddd5146f4b97' 
  AND token = 'Ti4vxPVs0XHGCy/t8GxZmhar8FfId8jt1qEj6ZwN+Uk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}