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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '645b135d827104cbdcc6ba865d64875784a4d7304fd3d01338b7a595d522a285' 
  AND token = '3UwLQ2r57etaw2fUejn/MwquhowIfDF/3DjSmim4/OI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}