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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '36f1bb3718ae8e287668cce3e70d2d1bded373c3351ce7640d628c8833c4fec7' 
  AND token = 'DrrSBX6uIG6sUyL1T6NSSnlYTd+RwR6jfE86ZIeb1LA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}