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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0337546e08b383a5f61b8fce3d6ebc8d71b312bd69afb45e38d308fbccb6bfa9' 
  AND token = 'dVeRQaldqpGTR8+B+eSPWdzpqjI4xk7TAH7vq5dD6zs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}