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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dc15ff1dc743ce5de5a8f7cc8dfe0ff199375c3fe7e09e85000636303df66d68' 
  AND token = 'RGy+D6I9PRjM9zvpXD+2ejc49mDIXZW+mO9yJTKmpMM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}