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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '218c90b0bea53be3ecf4c564c1ecf7a1367278ee9a8127ac479bd8871d55a02a' 
  AND token = 'Dc0c+/JILJTST14rmQ81wUUSgjyT3HGFRy7Mxkvj+3o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}