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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ad741cb08aa9376bf2fc5dc15c2f8f11fbe30a7a543b749a00dac452a7d693cf' 
  AND token = 'VHOkEDKrCxVBjB7XKUf8m/QoK8IIpkF9sCtDjMvdPp4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}