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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e0c8140a7a7f4f25803c774533e167ab82a0a65879347f8568bbb18dabfa6e8' 
  AND token = 'SCW9F5kdpzibbg0Afd5gnyFsVDG7yI/3Pz5Hrw/lcWQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}