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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f18f90500744af7621f410940749473e65ae1e955e0dba114673afbd9d75042f' 
  AND token = 'S2jsLQye/8PjqWKHLZrMNikZj+xl/F0PE1pV6OflPCY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}