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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4f1c7342fd460e9650f294cdc68a0fd85261611520302464083df7d15654184b' 
  AND token = '2pwHiVYqGRt/3PAw27TJIrZN0U3tCg6qW1YHiEDj3ro=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}