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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '67a2b22f234056f85dbd52e5779d6b0794e9e847503169954e0fc8d03f70b2c9' 
  AND token = 'eU3a/05RdoB5yoy9CNhOFychK6x2aCW5g0aArUbPO9I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}