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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1a3e04dc4ea7e5e9d85a425fd7d1b5e19963162b8f364edac5f26d7b587c8505' 
  AND token = 'mf+l5/CUYS2L+UzLGIjdup+GrnQW+T8WZw0TOImnaQ4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}