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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '76c271f7393c1813fe1addf041415e5449d58757112fd01fa1bc4bdfe9e14243' 
  AND token = '7EqSpDLZOENUtQjCScinaYQkukc0gHth4JvjSt72IjI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}