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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'afd110455730e07476f5f30120758a1798926dda7e5ffd7f080311f3e9d93ad9' 
  AND token = 'RJb4J+hCibXWpZk7XuoMRIZlrcSxNf88O3DlSch9zCA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}