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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aafdf73e959ee7a1c403d3eaf647fc350544289c75b2f8095baf0de16caf8c25' 
  AND token = 'AmY/kJACxRn6C6z+JDSkb0FbSYprD0KJW5IO0cZoEnY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}