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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '77ec4a10fabc477a36409d1c422ed2a84f9f12429985df7bacd6d840689fde32' 
  AND token = 'WJPvbI9TjgdZP2+3sk34GbTQFJBLQiFYJ5cbdWRj2Dk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}