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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ea4dadfa81dabc27a925da5de56b21bbdf3e0d3142f218b73b84799005e0de6c' 
  AND token = 'ex1wtm58R8m6Ols5vwVQoJaXubPZTJft8gKammQuwLg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}