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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '20114a243a51ac225ced037c3564167b471e2f7f212f339d3ddd1d56d8fd4b10' 
  AND token = '4tR6IGSRJf0Pl5To5mNhVI1KrEa4Y0fvxEQpEZUHmhs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}