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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7e375bd4a78a5a5bf7c5e778b56be219b4d9e25dd5e730b1ba152b4c97068276' 
  AND token = 'rxvP4zGgi0RsETNxcZhk7E5vlwZMssv4qYHSkvXJ0Vo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}