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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a57a22562961efd5fbe7f150c26be049fce81f4dc2cea44833fc5aa679b289a7' 
  AND token = 'zvUOJ9vZ7IJafybj6angLFwp+Y6D7cH2+0NkZ4oAso8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}