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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1da43405fbfcfe3df62bc756b75bd96fe06cb1d7eaf1357af0ac264d35da7c28' 
  AND token = 'EwnTS3VfWBMy+iGM2px4eOKnR3qbLzxYAjCx5UkMl5U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}