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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '881654d7f4e53856f56d5cbe62fafc6de0a26ecd9d02c7cdad94e560155b20b3' 
  AND token = 'kc7hyErkBp+E5yLrwrQxuYnLzs43mKCvEiXUWAj0f98=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}