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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f72249b3b96668b8874c7e12150cc50b878b197f15dc03086a9d7098c82370c5' 
  AND token = 'aCAGVB1WEBxnd08ERl42LYf0H7YodWdNSIq5fXwW+Tw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}