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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a1ebcff13ae269853bf28d9092be528169a7f64b88276be40849214478973b18' 
  AND token = 'JlPJr7AuJYm/nNoQLeqxRcrdOaSO6isdSHy8IF3RMqs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}