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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '25914e088fba78bca3d737f5b91817aa273d2b9895e5d7b4fbf45bafae36c884' 
  AND token = '2+mvAI0pII2nVzr44UDLynrn4K6G+bv6WSukg5aCalU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}