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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d0037d8051d96b4e10ce90082e996ae98db6ff53eb7d09c13a3994780e4325e' 
  AND token = 'hOo+uSEwQVq5NO508WaP1SBvi53y49fLiqCLzzZgZ+c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}