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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '173a0f8f67e19aeec0bf2da3c39b0326c1d2cd9fee883aa3f444443d170d6b54' 
  AND token = '0a0T7LK0EE49LSRMCvwHEL43G+W2FMihV9nIjgrAH/o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}