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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a644bb1971087c75b7dec120d8744fb5708261ad4aebc3d745c07880df747702' 
  AND token = 'vN990ywHoPZ02R7do8vn3f4It9YGqEIMR2bCu8B/E3U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}